Nora Speer, Holger Fröhlich and Andreas Zell
Functional Grouping of Genes Using Spectral Clustering and Gene Ontology
Abstract
With the invention of high throughput methods, researchers are capable
of producing large amounts of biological data. During the analysis
of such data the need of a functional grouping of genes arises. In
this paper, we propose a new method based on spectral clustering for
the partitioning of genes according to their biological function. The
functional information is based on Gene Ontology annotation, a mechanism
to capture knowledge in a shareable and computer processable form.
Our functional cluster method promises to automatize, speed up and
therefore improve biological data analysis.
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BibTeX
@conference{SpeerFroe05GOClust,
AUTHOR="N. Speer and H. Fröhlich and A. Zell",
TITLE="{Functional Grouping of Genes Using Spectral Clustering and Gene Ontology}",
BOOKTITLE="Proc. Int. Joint Conf. on Neural Networks",
PAGES="298 - 303",
YEAR=2005
}