Andreas Dräger

Background

  • 1991 - 1999: Gymnasium (high school) “Am Markt” in Hettstedt
  • 2000 - 2006: Studies of Bioinformatics at the Martin-Luther-University Halle-Wittenberg
  • 2001: Internship at the Max Planck Institute for Molecular Genetics, Berlin, at the group of Dr. Richard Reinhard
  • 2004: Internship at the University of Illinois at Chicago, United States, Microbiology and Immunology at the group of Prof. Dr. Simon Silver
  • since February 2006: Research assistant at the Center for Bioinformatics (ZBIT), University of Tübingen

Research Interests

  • Evolutionary algorithms
  • Metabolic and gene-regulatory networks
  • Systems biology
  • Application and developement of BioJava and BioSQL

Current Projects

  • HepatoSys: Systems biology of the human liver, especially detoxification processes in conjunction with statin treatment
  • German National Genome Research Network (NGFN-Plus): medical genome research with focus on Parkinson's disease
  • Inference of gene-regulatory networks
  • Identification and analysis of metabolic networks given experimental data

Publications

ModuleMaster: a new tool to decipher transcriptional regulatory networks
Clemens Wrzodek, Adrian Schröder, Andreas Dräger, Dierk Wanke, Kenneth W. Berendzen, Marcel Kronfeld, Klaus Harter, and Andreas Zell
Biosystems 2009, In Press, accepted.
[BibTeX], [pdf]
On the Benefits of of Multimodal Optimization for Metabolic Network Modeling
Marcel Kronfeld, Moritz Aschoff, Andreas Dräger, and Andreas Zell
German Conference on Bioinformatics (GCB 2009), Halle (Saale), Germany, pp. 191-200, 2009.
[BibTeX], [pdf]
BowTieBuilder: modeling signal transduction pathways
Jochen Supper, Lucía Spangenberg, Hannes Planatscher, Andreas Dräger, Adrian Schröder, and Andreas Zell
BMC Systems Biology 2009, (30 June 2009).
[BibTeX], [pdf]
SBML2LaTeX: Conversion of SBML files into human-readable reports
Andreas Dräger, Hannes Planatscher, Dieudonné Motsou Wouamba, Adrian Schröder, Michael Hucka, Lukas Endler, Martin Golebiewski, Wolfgang Müller, and Andreas Zell
Bioinformatics 2009, (23 March 2009).
[BibTeX], [pdf]
Modeling metabolic networks in C. glutamicum: a comparison of rate laws in combination with various parameter optimization strategies
Andreas Dräger, Marcel Kronfeld, Michael Johannes Ziller, Jochen Supper, Hannes Planatscher, Jørgen Barsett Magnus, Marco Oldiges, Oliver Kohlbacher, and Andreas Zell
BMC Systems Biology 2009, 3:5 (14 January 2009).
[BibTeX], [pdf]
BioJava: an Open-Source Framework for Bioinformatics
Richard C. G. Holland, Thomas Down, Matthew Pocock, Andreas Prlić, David Huen, Keith James, Sylvain Foisy, Andreas Dräger, Andy Yates, Michael Heuer, and Mark J. Schreiber
Bioinformatics 2008, (8 August 2008).
[BibTeX], [pdf]
SBMLsqueezer: a CellDesigner plug-in to generate kinetic rate equations for biochemical networks
Andreas Dräger, Nadine Hassis, Jochen Supper, Adrian Schröder, and Andreas Zell
BMC Systems Biology 2008, 2:39 (30 April 2008).
[BibTeX], [pdf]
Benchmarking Evolutionary Algorithms on Convenience Kinetics Models of the Valine and Leucine Biosynthesis in C. glutamicum
Andreas Dräger, Marcel Kronfeld, Jochen Supper, Hannes Planatscher, Jørgen Barsett Magnus, Marco Oldiges, and Andreas Zell
IEEE Congress on Evolutionary Computation (CEC 2007), Singapore, pp. 896-903, 2007.
[BibTeX], [pdf]
Comparing Various Evolutionary Algorithms on the Parameter Optimization of the Valine and Leucine Biosynthesis in Corynebacterium glutamicum
Andreas Dräger, Jochen Supper, Hannes Planatscher, Jørgen Barsett Magnus, Marco Oldiges, and Andreas Zell
IEEE Congress on Evolutionary Computation (CEC 2007), Singapore, pp. 620-627, 2007.
[BibTeX], [pdf]
Infering Gene Regulatory Networks by Machine Learning Methods
Jochen Supper, Holger Fröhlich, Christian Spieth, Andreas Dräger, and Andreas Zell
Series on Advances in Bioinformatics and Computational Biology, vol 5, pp. 267-276, Asia-Pacific Bioinformatics Conference (APBC 2007), Hong Kong, 2007.
[BibTeX], [pdf]

Selected Presentations

Inferring Genetic Networks from Gene Expression Data
Andreas Dräger, Nora Speer, Christian Spieth, Jochen Supper, and Andreas Zell
Biotechnica 2009, Internationale Messe für Biotechnologie, Hannover, Germany, (8 October 2009).
Metabolic modeling of Corynebacterium glutamicum: a comparison of rate lwas in combination with various parameter optimisation strategies
Andreas Dräger, Marcel Kronfeld, Michael Johannes Ziller, Jochen Supper, Hannes Planatscher, Jørgen Barsett Magnus, Marco Oldiges, Oliver Kohlbacher, and Andreas Zell
ACHEMA 2009, 29. internationaler Ausstellungskongress für chemische Technik, Umweltschutz und Biotechnologie, Frankfurt am Main, Germany, (13 May 2009).

Selected Posters

A Tool for Interactive Comparative Sequence Analysis
Andreas Dräger, Dietrich H. Nies, and Stefan Posch
German Conference on Bioinformatics (GCB) 2006, Tübingen, Germany
[pdf]

Theses

Automatic and comparative analysis of bacterial genomes with main focus on Ralstonia/Cupriavidus species and related Proteobacteria ("Automatische und vergleichende Analyse bakterieller Genome mit Schwerpunkt auf Ralstonia/Cupriavidus Arten sowie verwandten Proteobakerien"), [English summary; pdf]
Diplomarbeit, Martin-Luther-University Halle-Wittenberg, Department of Bioinformatics and Pattern Recognition, Prof. Dr.-Ing. Stefan Posch, and Department of Molecular Microbiology, Prof. Dr. Dietrich H. Nies, 2005
Search for frequent protein fragments considering mutations and gaps ("Suche häufiger Proteinfragmente unter Berücksichtigung von Mutationen und Lücken")
Projektarbeit, Martin-Luther-University Halle-Wittenberg, Department of Databases and Information Systems, Dr. Alexander Hinneburg, 2004

Address, Phone, Fax, E-Mail

Eberhard-Karls-Universität Tübingen
Wilhelm-Schickard-Institut für Informatik
Lehrstuhl Rechnerarchitektur
Sand 14
72076 Tübingen
Germany

Phone:     +49 70 71 29-7 04 36
Fax: +49 70 71 29-50 91
E-Mail: andreas.draeger at uni-tuebingen.de